Prof Dave Lyons and Dr Line Kegel publish book on protocols for oligodendrocytes research. ‘Oligodendrocytes: Methods and Protocols’, a book edited by Prof Dave Lyons and Dr Line Kegel from the University of Edinburgh looks at the study of oligodendrocytes through in vitro and in vivo techniques, using multiple model organisms and approaches. Various researchers from the University of Edinburgh, including the MRC Centre for Regenerative Medicine, have contributed chapters. The 22 book chapters cover topics such as fundamental molecular analyses of oligodendrocytes and myelin; the study of cellular and molecular mechanisms of demyelination and remyelination in vivo; oligodendrocyte formation, in vitro, ex vivo, and in vivo molecular-cellular-electrophysiology-based techniques; homeostasis, and disruption in zebrafish and Xenopus; and parallel system-level imaging of animal and human models. Written in the Methods in Molecular Biology series format, each protocol chapter includes an introduction to the topic covered, and describes necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. The book is a valuable reference guide that highlights the expansive and fast-paced nature of research into oligodendrocyte biology underlying health and function. Oligodendrocytes: Methods and Protocols, edited by David A. Lyons and Linde Kegel (Springer Protocols, 2019) This article was published on 2024-08-22
