Human aortic valve

Using microPET/CT images to understand the mechanisms underlying calcification of human aortic valves.

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human aortic valve PET/CT image

Our preclinical PET/CT scanner is capable of acquiring images with a much higher sensitivity and resolution than a clinical PET scanner, allowing in-depth analysis of oartic calcification in human tissues. (A) MicroCT image co-registered to microPET image demonstrating mismatch between 18F-NaF uptake distribution and CT density in a severely calcified human aortic valve. (B) Volume rendering of same human aortic valve shown in (A).