2020

Publications

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis. Suchacki KJ, Tavares AAS, Mattiucci D, Scheller EL, Papanastasiou G, Gray C, Sinton MC, Ramage LE, McDougald WA, Lovdel A, Sulston RJ, Thomas BJ, Nicholson BM, Drake AJ, Alcaide-Corral CJ, Said D, Poloni A, Cinti S, Macpherson GJ, Dweck MR, Andrews JPM, Williams MC, Wallace RJ, van Beek EJR, MacDougald OA, Morton NM, Stimson RH, Cawthorn WP.Nat Commun. 2020 Jun 18;11(1):3097.

Rapidly (and Successfully) Translating Novel Brain Radiotracers From Animal Research Into Clinical Use. Shaw RC, Tamagnan GD, Tavares AAS.Front Neurosci. 2020 Oct 1;14:871. doi: 10.3389/fnins.2020.00871. eCollection 2020.PMID: 33117115 Free PMC article. Review.

Ex vivo ¹⁸F-fluoride uptake and hydroxyapatite deposition in human coronary atherosclerosis.Moss AJ, Sim AM, Adamson PD, Seidman MA, Andrews JPM, Doris MK, Shah ASV, BouHaidar R, Alcaide-Corral CJ, Williams MC, Leipsic JA, Dweck MR, MacRae VE, Newby DE, Tavares AAS, Sellers SL.Sci Rep. 2020 Nov 19;10(1):20172.

Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers. Schantl AE, Verhulst A, Neven E, Behets GJ, D'Haese PC, Maillard M, Mordasini D, Phan O, Burnier M, Spaggiari D, Decosterd LA, MacAskill MG, Alcaide-Corral CJ, Tavares AAS, Newby DE, Beindl VC, Maj R, Labarre A, Hegde C, Castagner B, Ivarsson ME, Leroux JC.Nat Commun. 2020 Feb 5;11(1):721.

Characterisation of an atherosclerotic micro-calcification model using ApoE^-/- mice and PET/CT. MacAskill MG, McDougald W, Alcaide-Corral C, Newby DE, Tavares AAS, Hadoke PWF, Wu J.Int J Cardiol Heart Vasc. 2020 Nov 15;31:100672. doi: 10.1016/j.ijcha.2020.100672. eCollection 2020

Preclinical dosimetry models and the prediction of clinical doses of novel positron emission tomography radiotracers.Garrow AA, Andrews JPM, Gonzalez ZN, Corral CA, Portal C, Morgan TEF, Walton T, Wilson I, Newby DE, Lucatelli C, Tavares AAS.Sci Rep. 2020 Sep 29;10(1):15985. doi: 10.1038/s41598-020-72830-w.

Non-invasive in vivo imaging of acute thrombosis: development of a novel factor XIIIa radiotracer. Andrews JPM, Portal C, Walton T, Macaskill MG, Hadoke PWF, Alcaide Corral C, Lucatelli C, Wilson S, Wilson I, MacNaught G, Dweck MR, Newby DE, Tavares AAS.Eur Heart J Cardiovasc Imaging. 2020 Jun 1;21(6):673-682. doi: 10.1093/ehjci/jez207.

Standardization of Preclinical PET/CT Imaging to Improve Quantitative Accuracy, Precision, and Reproducibility: A Multicenter Study. McDougald W, Vanhove C, Lehnert A, Lewellen B, Wright J, Mingarelli M, Corral CA, Schneider JE, Plein S, Newby DE, Welch A, Miyaoka R, Vandenberghe S, Tavares AAS.J Nucl Med. 2020 Mar;61(3):461-468. doi: 10.2967/jnumed.119.231308. Epub 2019 Sep 27..

Quantification of Macrophage-Driven Inflammation During Myocardial Infarction with ¹⁸F-LW223, a Novel TSPO Radiotracer with Binding Independent of the rs6971 Human Polymorphism. MacAskill MG, Stadulyte A, Williams L, Morgan TEF, Sloan NL, Alcaide-Corral CJ, Walton T, Wimberley C, McKenzie CA, Spath N, Mungall W, BouHaidar R, Dweck MR, Gray GA, Newby DE, Lucatelli C, Sutherland A, Pimlott SL, Tavares AAS.J Nucl Med. 2021 Apr;62(4):536-544. doi: 10.2967/jnumed.120.243600. Epub 2020 Aug 28.

Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy. Jacek Kwiecinski, Ross J. Lennen, Gillian A. Gray, Gary Borthwick, Lyndsey Boswell, Andrew H. Baker, David E. Newby, Marc R. Dweck & Maurits A. Jansen. Journal of Cardiovascular Magnetic Resonance volume 22, Article number: 57 (2020)

miR-96 and miR-183 differentially regulate neonatal and adult postinfarct neovascularization. Castellan RF, Vitiello M, Vidmar M, Johnstone S, Iacobazzi D, Mellis D, Cathcart B, Thomson A, Ruhrberg C, Caputo M, Newby DE, Gray GA, Baker AH, Caporali A, Meloni M. JCI Insight. 2020 Jul 23;5(14):134888.

Eosinophil Deficiency Promotes Aberrant Repair and Adverse Remodeling Following Acute Myocardial Infarction. Iqbal S. Toor, Dominik Rückerl, Iris Mair, Rob Ainsworth, Marco Meloni, Ana-Mishel Spiroski, Cecile Benezech, Jennifer M. Felton, Adrian Thomson, Andrea Caporali, Thomas Keeble, Kare H. Tang, Adriano G. Rossi, David E. Newby, Judith E. Allen and Gillian A. Gray. JACC: Basic to Translational Science

Lucy E Kershaw , David ML Lilburn , Maurits A Jansen , Andrew R Bond , Salamah M Alwahsh , Pilar Jimenez Royo , Antonella Napolitano, Philip Murphy, Alexandra Roberts, Rob Janiczek , Shareen Forbes , Scott IK Semple . Manganese-enhanced MRI: Comparison of agents in the rat pancreas. J Magn Res Open 1, December 2019, 100002.

Starkey Lewis P, Campana L, Aleksieva N, Cartwright JA, Mackinnon A, O'Duibhir E, Kendall T, Vermeren M, Thomson A, Gadd V, Dwyer B, Aird R, Man TY, Rossi AG, Forrester L, Park BK, Forbes SJ. Alternatively activated macrophages promote resolution of necrosis following acute liver injury. J Hepatol. 2020 Mar 11: S0168-8278(20)30133-1.

Moran CM, Thomson A. Preclinical Ultrasound Imaging—A Review of Techniques and Imaging Applications. Front. Phys., 05 May 2020.

Spath N, Tavares A, Gray GA, Baker AH, Lennen RJ, Alcaide-Corral CJ, Dweck MR, Newby DE, Yang PC, Jansen MA, Semple SI. Manganese-enhanced T(1) mapping to quantify myocardial viability: validation with (18)F-fluorodeoxyglucose positron emission tomography. Sci Rep. 2020 Feb 6;10(1):2018.

Schantl AE, Verhulst A, Neven E, Behets GJ, D'Haese PC, Maillard M, Mordasini D, Phan O, Burnier M, Spaggiari D, Decosterd LA, MacAskill MG, Alcaide-Corral CJ, Tavares AAS, Newby DE, Beindl VC, Maj R, Labarre A, Hegde C, Castagner B, Ivarsson ME, Leroux JC. Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers. Nat Commun. 2020 Feb 5;11(1):721.

Jones NK, Stewart K, Czopek A, Menzies RI, Thomson A, Moran CM, Cairns C, Conway BR, Denby L, Livingstone DEW, Wiseman J, Hadoke PW, Webb DJ, Dhaun N, Dear JW, Mullins JJ, Bailey MA. Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation. Hypertension. 2020 May;75(5):1213-1222.

Castellan RFP, Thomson A, Moran CM, Gray GA. Electrocardiogram-gated Kilohertz Visualisation (EKV) Ultrasound Allows Assessment of Neonatal Cardiac Structural and Functional Maturation and Longitudinal Evaluation of Regeneration After Injury. Ultrasound Med Biol. 2020 Jan;46(1):167-179.

DEVELOPING A WIRE-INJURY MODEL OF CALCIFIC AORTIC STENOSIS 1 Holly Woodward, 1 Adrian Thomson, 2 Vicky Macrae, 3 Patrick Hadoke. 1 University of Edinburgh; 2 The Roslin Institute, University of Edinburgh; 3 Centre for Cardiovascular Science, University of Edinburgh 10.1136/heartjnl-2020-BCS.18

This article was published on 2024-08-22