PET/CT

The microPET/CT laboratory was established in 2014 and offers state-of-the-art facilities for molecular imaging research using different radiotracers, as well as, high resolution anatomical computed tomography (CT) images.

Image
Preclinical PET/CT facility

Resources available in the microPET/CT laboratory allow for in vivo imaging studies in rodents targeting different systems and various research questions, as well as, ex vivo/in vitro imaging of human tissue samples and organs.

 

MicroPET/CT system:

  • Mediso nanoPET/CT, Mediso Medical Imaging Systems, Budapest, Hungary  
  • Axial field of view (FOV): 28 cm
  • PET spatial resolution: 1.02 mm (axial cFOV, FWHM)
  • PET sensitivity: 8%
  • CT spatial resolution: <30μm at 10% modulation transfer function (MTF)

 

The preclinical PET/CT imaging facilities are complemented by laboratories dedicated to cell, tissue and organ radiolabelling for subsequent tracking or imaging using the microPET/CT system.

Through our active collaboration with the radiochemistry department at the clinical research imaging centre (CRIC), a wide range of 18F- and 11C-labelled radiotracers can be produced on site for preclinical PET/CT imaging. Examples include:

  • 18F-FDG for imaging glucose metabolism;
  • 18F-NaF for imaging crystals of hydroxyapatite;
  • 18F-L-Dopa for imaging dopamine turnover;  
  • 18F-Fluorocholine for imaging cellular membrane phospholipids;

Others available upon consultation.

 

Dr Adriana Tavares

Head Preclinical PET/CT Facility

Contact details

Examples of Studies using our PET/CT Equipment