2017

Publications

Kitamura A, Manso Y, Duncombe J, Searcy J, Koudelka J, Binnie M, Webster S, Lennen R, Jansen M, Marshall I, Ihara M, Kalaria RN, Horsburgh K. Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion. Sci Rep. 2017 Jun 27;7(1):4299

McDougald WA, Collins R, Green M, Tavares AAS. “High dose microCT does not contribute towards improved microPET/CT image quantitative accuracy and can limit longitudinal scanning of small animals”. Frontiers in Physics. 2017; 5:50.  

Rabell Montiel A, Browne JE, Pye SD, Anderson TA, Moran CM. Broadband Acoustic Measurement of an Agar-Based Tissue-Mimicking-Material: A Longitudinal Study. Ultrasound Med Biol. 2017 Jul;43(7):1494-1505.

Coan PM, Barrier M, Alfazema N, Carter RN, Marion de Procé S, Dopico XC, Garcia Diaz A, Thomson A, Jackson-Jones LH, Moyon B, Webster Z, Ross D, Moss J, Arends MJ, Morton NM, Aitman TJ. Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome. Hypertension. 2017 Jul 24.

MacAskill MG, Zmuda F, Blair A, Lucatelli C, Dweck MR, Gray GA, Newby DE, Sutherland A, Pimlott SL, Tavares AAS (2017). Binding affinity profiles of isoquinoline carboxamide and phenoxyphenyl acetamide-based TSPO PET ligands in human brain and heart. J Nuc Med. 58 (S1):478.

Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P. PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet. 2017 May 4;100(5):706-724.

Bappoo N, Kelsey LJ, Parker L, Crough T, Moran CM, Thomson A, Holmes MC, Wyrwoll CS, Doyle BJ. Viscosity and haemodynamics in a late gestation rat feto-placental arterial network. Biomech Model Mechanobiol. 2017 Mar 3. [Epub ahead of print]

MacAskill MG, Tavares AS, Wu J, Lucatelli C, Mountford JC, Baker AH, Newby DE, Hadoke PW. PET Cell Tracking Using (18)F-FLT is Not Limited by Local Reuptake of Free Radiotracer. Sci Rep. 2017 Mar 13;7:44233.

Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, Mungall W, Kendall TJ, Thomson A, Lennen RJ, Jansen MA, Moran CM, Pellicoro A, Ramachandran P, Shaw I, Aucott RL, Severin T, Saini R, Pak J, Yates D, Dongre N, Duffield JS, Webb DJ, Iredale JP, Hayes PC, Fallowfield JA. Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial. PLoS Med. 2017 Feb 28;14(2):e1002248

Thompson RAA, Dickinson RS, Murphy F, Thomson JP, Marriott HM, Tavares A, Willson J, Williams L, Lewis A, Mirchandani A, Dos Santos Coelho P, Doherty C, Ryan E, Watts E, Morton NM, Forbes F, Stimson RH, Hameed AG, Arnold N, Preston JA, Lawrie A, Finisguerra V, Mazzone M, Sadiku P, Goveia J, Taverna F, Carmeliet P, Foster S, Chilvers ER, Cowburn AS, Dockrell DH, Johnson RS, Meehan RR, Whyte MKB and  Walmsley SR. Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism. Science Immunology 2017. 10; 2(8). pii: eaal2861. 

Richardson R, Batchen E, Thomson A, Darroch R, Pan X, Rog-Zielinska E, Wyrzykowska W, Scullion K, Al-Dujaili EA, Diaz M, Moran C, Kenyon CJ, Gray GA, Chapman K. Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis. J Endocrinol. 2017 Jan 5

Sharkey J, Starkey Lewis PJ, Barrow M, Alwahsh SM, Noble J, Livingstone E, Lennen RJ, Jansen MA, Carrion JG, Liptrott N, Forbes S, Adams DJ, Chadwick AE, Forbes SJ, Murray P, Rosseinsky MJ, Goldring CE, Park BK. Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labeling in macrophages for magnetic resonance-based detection in vivo. Cytotherapy. 2017  Feb 15. pii: S1465-3249(17)30005-1.

Duncombe J, Lennen RJ, Jansen MA, Marshall I, Wardlaw JM, Horsburgh K. Ageing  causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis. Neuropathol Appl Neurobiol. 2016 Dec 31, [Epub ahead of print]

Merrifield GD, Mullin J, Gallagher L, Tucker C, Jansen MA, Denvir M, Holmes WM. Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. Magn Reson Imaging. 2016 Oct 14;37:9-15. [Epub ahead of print]