Edinburgh Imaging's completed stroke projects. HTML Completed projects Title Description ENCHANTED Enhanced Control of Hypertension & Thrombolysis Stroke Study Randomised-controlled trial comparing the following acute treatments for ischaemic stroke: Low dose IV alteplase versus standard dose Intensive blood pressure lowering versus standard care IST-3 Third International Stroke Trial Randomised-controlled trial of IV alteplase versus control. Main publication, trial protocol. Imaging substudy of arterial patency & brain perfusion. Main publication, trial protocol PISCES-II Phase IIa clinical trial in stroke disability PISCES II is a single arm, open-label study in patients living with disability resulting from ischaemic stroke. PISTE Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) A randomised controlled clinical trial of adjunctive mechanical thrombectomy compared with intravenous thrombolysis in patients with acute ischaemic stroke due to an occluded major intracranial vessel. PREVENT-SVD (LACI-1) Preventing cognitive decline & dementia from cerebral small vessel disease. (LACunar Intervention Trial-1) The trial hypothesis is to test whether a much larger scale study testing the effects of Cilostazol & ISMN on preventing brain damage from small vessel disease will be feasible. RIGHT-2 Rapid intervention with Glyceryl trinitrate in Hypertensive stroke trial-2 GTN in acute stroke. This article was published on 2024-08-22
HTML Completed projects Title Description ENCHANTED Enhanced Control of Hypertension & Thrombolysis Stroke Study Randomised-controlled trial comparing the following acute treatments for ischaemic stroke: Low dose IV alteplase versus standard dose Intensive blood pressure lowering versus standard care IST-3 Third International Stroke Trial Randomised-controlled trial of IV alteplase versus control. Main publication, trial protocol. Imaging substudy of arterial patency & brain perfusion. Main publication, trial protocol PISCES-II Phase IIa clinical trial in stroke disability PISCES II is a single arm, open-label study in patients living with disability resulting from ischaemic stroke. PISTE Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) A randomised controlled clinical trial of adjunctive mechanical thrombectomy compared with intravenous thrombolysis in patients with acute ischaemic stroke due to an occluded major intracranial vessel. PREVENT-SVD (LACI-1) Preventing cognitive decline & dementia from cerebral small vessel disease. (LACunar Intervention Trial-1) The trial hypothesis is to test whether a much larger scale study testing the effects of Cilostazol & ISMN on preventing brain damage from small vessel disease will be feasible. RIGHT-2 Rapid intervention with Glyceryl trinitrate in Hypertensive stroke trial-2 GTN in acute stroke.
