The Radiochemistry facility at the University of Edinburgh houses a cyclotron with supporting radiochemistry suites to create both GMP & research PET radiotracers. Image Overview We can produce radiochemicals labelled with PET isotopes (18F, 11C & 15O). This allows us to: Conduct PET imaging experiments & autoradiography with chemically-identical compounds Develop fully translational tracers Adopt locally existing radiolabelled tracers to GMP standards, for use in human in clinical studies From Jan-Mar 2019, we are expanding our production facility to increase capacity for GMP radiopharmaceutical delivery. Location The EIF Radiochemistry is co-located with our EIF QMRI which allows for close collaboration with & efficient transfer of radiochemicals to the: PET-MR 3.0T Siemens Healthcare & Biograph mMR (the only PET-MR system in Scotland) PET-CT 64 slice GE Healthcare & Discovery 710 PET-CT 128 slice Siemens Healthcare Biograph mCT The EIF Radiochemistry is also in very close proximity to our EIF Preclinical which also allows for close collaboration with & efficient transfer of radiochemicals to the: PET-CT Mediso nanScan In addition to providing tracers for local use within the Edinburgh Imaging Facilities, we also supply more remote PET centres. Expertise In addition to the above, we have local expertise in: Data reconstruction Image analysis Kinetic modelling HPLC metabolite quantification including Arterial blood sampling Input function measurement Radiochemistry Cyclotron GE Healthcare EIF QMRI GMP Radiochemistry Suite EIF QMRI Relevant links 09 May 22. JNM Editor’s Choice Award 25 Oct 21. Edinburgh Imaging Radiochemistry - NHS Lothian 18 Oct 21. Edinburgh Imaging Radiochemistry - SALTIRE II 14 Oct 21. DPUK Harmonisation study 11 Oct 21. Edinburgh Imaging Radiochemistry - GP1 04 Oct 21. Edinburgh Imaging Radiochemistry - FAPI 02 Aug 21. Radiochemistry 18F-FDG production milestone 06 Feb 20. Featured Paper. Manganese-enhanced T1 mapping to quantify myocardial viability: validation with 18F-fluorodeoxyglucose positron emission tomography. 14 Sep 18. Edinburgh Imaging Facilities Useful links Please link to the short url for our Edinburgh Imaging Facility radiochemistry webpage: www.ed.ac.uk/edinburgh-imaging/eif-radiochemistry This article was published on 2024-08-22