As the Edinburgh Imaging Radiochemistry facility temporarily closes for refurbishment, we look back at the facility's success with 18F-glycoprotein 1 (GP1) radiotracers. Image 18F-GP1 signal is increased in regions of prosthetic valve thrombus on autoradiography (left) & microPET-CT (middle), but also on bioprosthetic valve leaflets with no CT evidence of thrombus (right) The Edinburgh Imaging Radiochemistry facility was opened in 2010 & currently houses a cyclotron with supporting radiochemistry suites to create both GMP & research PET radiotracers. The EI Radiochemistry facility has now temporarily closed for refurbishment. 18F-GP1 is a derivative of elarofiban with a high affinity for activated platelet glycoprotein IIb & IIIa. It has promising in vivo characteristics for thrombus (clot) imaging. Edinburgh Imaging has carried out the first cardiac & neurological applications of this imaging tracer. The Edinburgh Imaging facilities & radiochemistry team are integral to 18F-GP1 studies, both for production of the imaging tracer in our radiochemistry as well as the groundbreaking imaging using PET-CT & PET-MR in our Edinburgh Imaging QMRI facility. We are currently involved with three 18F-GP1 studies: Biothrombus iThrombus & Myothrombus Relevant links Edinburgh Imaging Edinburgh Imaging facilities Edinburgh Imaging facility radiochemistry Edinburgh Imaging facility QMRI Edinburgh Imaging equipment What is a PET-CT scan? What is a PET-MR scan? 04 Oct 21. Edinburgh Imaging Radiochemistry - FAPI 02 Aug 21. Radiochemistry 18F-FDG production milestone 27 Apr 21. Edinburgh Imaging FAPI accomplishment Social media tags & titles As the Edinburgh Imaging Radiochemistry facility temporarily closes for refurbishment, we look back at the facility's success with 18F-glycoprotein 1 (GP1) radiotracers. @EdinUniMedicine @EdinburghBQ Publication date 05 Oct, 2021
