HepaT1ca

We use multiple functional imaging parameters obtained in a single MR scan.

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TitleHepaT1ca
Description

We use multiple functional imaging parameters obtained in a single MR scan to describe:

  • liver fibrosis
  • iron content
  • fat content
  • perfusion (via non-invasive assessment of portal blood flow)

This assesses non-invasively, progression of liver disease & response to therapy or following surgery.

Applications to date in:

  • cirrhosis
  • non-alcoholic fatty liver disease
  • macrophage therapy
  • liver islet therapy
  • liver transplant
  • acute liver insult

This type of non-invasive test can help to prevent repeated liver biopsies, while also assessing liver heterogeneity in a manner which liver biopsies cannot.  

This is great for improved patient comfort and for assessing early responses to therapy

Status
  • Active - recruitment has closed & analysis has begun
PI
Edinburgh Imaging Collaborator
Disease
Facility / resource
Project type 
Funding