The Brain Images of Normal Subjects (BRAINS) imagebank is a searchable, living database of images & clinical information across the human lifespan. Image BRAINS Imagebank logo What is BRAINS? an integrated repository project / living imagebank hosted by the University of Edinburgh sponsored by the Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) collaborators contains data from 808 healthy volunteers 15 to 81 years of age from 7 projects in 3 centres new data will be added when available additional completed & ongoing studies of normal individuals from 1st to 10th decades are in preparation & will be included as they become available What is the BRAINS imagebank? an anonymised collection of images & associated clinical data collected from 'normal' individuals participating in research it includes several MR & structural sequences (e.g. T1, T2, T2* & FLAIR) available in DICOM (http://dicom.nema.org/) future addition of DTI planned images are linked to a wide range of ‘textual data’ including: age medical history physiological measures (e.g. blood pressure) medication use cognitive ability perinatal information for pre- / post-natal subjects the imagebank can be searched to include or exclude ranges of these variables to create better estimates of ‘what is normal’ at different ages What does BRAINS provide? sharing & archiving of detailed normal human brain imaging sharing & archiving of relevant phenotypic data data is already collected in studies of healthy volunteers across the life-course focus is in particular on extremes of age where variability is largest current emphasis on older age future plans to include perinatal imaging future plans to include other imaging which is under-represented in existing databanks Useful links Key publications: Developing an integrated image bank & metadata for large-scale research in cerebrovascular disease: our experience from the stroke image bank project. Frontiers ITC. 2016. doi.org/10.3389/fict.2016.00032 A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS). Neuroimage. 2017 144(B):299-304. doi: 10.1016/j.neuroimage.2016.01.027 Improving data availability for brain image biobanking in healthy subjects: practice-based suggestions from an international multidisciplinary working group. NeuroImage. 2017 153:399-409. doi.org/10.1016/j.neuroimage.2017.02.030 Other resources: BRAINS imagebank homepage Edinburgh DataShare for access to BRAINS image data Relevant links SINAPSE University of Edinburgh Brain & nervous system This article was published on 2024-08-22