Edinburgh Imaging's current small vessel disease projects. HTML Current projects Title Description INVESTIGATE-SVDs Imaging NeuroVascular, Endothelial & STructural Integrity in prepAration to TrEat Small Vessel Diseases A MRI study at 3T to assess blood brain barrier function, microvascular function, & perivascular flow. LACI-2 LACunar Intervention Trial-2 Assessment of safety & efficacy of cilostazol & isosorbide mononitrate to prevent recurrent lacunar stroke & progression of cerebral small vessel disease. Leducq Investigate the role of the enlarged perivascular space (PVS) in cerebral small vessel disease (SVD). Mild Stroke Study 3 Improve understanding of what makes small vessel disease (SVD) worsen (or perhaps improve) & identify novel targets for SVD prevention & therapy. SVDs@target Develop novel therapeutic treatments & finally contribute to the prevention of stroke & dementia TREAT-SVDs EffecTs of Amlodipine & other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases An interventional study to determine the effects of different blood pressure lowering agents on microvascular function in patients with distinct SVDs. This article was published on 2024-08-22
HTML Current projects Title Description INVESTIGATE-SVDs Imaging NeuroVascular, Endothelial & STructural Integrity in prepAration to TrEat Small Vessel Diseases A MRI study at 3T to assess blood brain barrier function, microvascular function, & perivascular flow. LACI-2 LACunar Intervention Trial-2 Assessment of safety & efficacy of cilostazol & isosorbide mononitrate to prevent recurrent lacunar stroke & progression of cerebral small vessel disease. Leducq Investigate the role of the enlarged perivascular space (PVS) in cerebral small vessel disease (SVD). Mild Stroke Study 3 Improve understanding of what makes small vessel disease (SVD) worsen (or perhaps improve) & identify novel targets for SVD prevention & therapy. SVDs@target Develop novel therapeutic treatments & finally contribute to the prevention of stroke & dementia TREAT-SVDs EffecTs of Amlodipine & other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases An interventional study to determine the effects of different blood pressure lowering agents on microvascular function in patients with distinct SVDs.